Tamoxifen is a non-hormonal drug that is an antagonist of estrogen. Once in the human body, its active component binds to a specific receptor and prevents the uptake of estrogen. Thus, Tamoxifen slows the growth of estrogen-dependent tumors. In addition, it has an effect similar to estrogen, has a beneficial effect on the state of the endometrium of the uterus, the musculoskeletal system, the level of cholesterol in the blood.
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Prescribe Tamoxifen at estrogen-dependent tumors of the breast, uterus, melanoma, carcinoma of the prostate, sarcomas and some other types of tumors. Also, this drug can be used for hormone replacement therapy after removal of the ovaries or in the absence of ovulation.
Produce Tamoxifen in pill form. Manual of drug reports that first assigned a lower dose, which, after a while, increases to necessary. The basic principle of the dosing Tamoxifen is the individual selection.
Not recommended treatment with Tamoxifen people with individual intolerance, in severe pathology of hematopoiesis. Diabetes, ophthalmic disorders, also should be cause for extreme caution during therapy with this medication. Separately, it should be noted that women in childbearing age, up until menopause, you should use a serious contraceptive measures without the use of hormonal contraceptive drugs. Dangerous for pregnancy are the period of therapy, Tamoksifenom and two months after its completion. Also, at this time is to breastfeed the baby.
Side effects and overdose of Tamoxifen.
The annotation of the medication indicated that the number of adverse effects from Tamoxifen is less than that of the hormonal drugs which also are used in the treatment of cancer. However, the described effects such as hot flushes, bleeding, itching – they are due to antiestrogen effect of the drug. Can occur common adverse effects – dyspepsia, edema, hair loss, and so on. The basic rule for correction of Tamoxifen therapy involving side effects is dose reduction. This drug should be accompanied by medical and laboratory control. Overdose cases are not described, but it is assumed the manifestation of the action similar to the action of estrogen. Measures should be taken symptomatic.
Reviews about Tamoxifen.
Since this medicine is used in treatment of such severe and complicated processes, such as cancer or hormonal disorders, including disruptions of menstrual cycle effects on the body of each patient is very individual and evaluate the impact of Tamoxifen on the reviews about it not quite right.
There are often questions about the impact of Tamoxifen on a particular symptom, its role in the development of a particular state. Discuss treatment comes in mind not to much because it is often about life or death of the patient.
However, there are egregious cases of the use of Tamoxifen – fans of bodybuilding, build muscle mass with the help of hormonal preparations. They quite often try to “hit estrogenic effect” of some anabolics this tool. It is worth noting that such an invasion of privacy in the private health – always ends in tears. If the consequences will not come soon, they must manifest itself throughout life.
It is obvious that in some conditions, Tamoxifen is required. And this fact practically excludes the evaluation approach – this drug is good or bad. The main thing is not to cripple themselves by thoughtless use of medicines, for the sake of some illusory goals.