Lisinopril is a drug which affects the vascular system and heart. The active substance of medicines called similarly refers to the pharmacological group of inhibitors. In other words, lisinopril prevents the conversion of angiotensin I to angiotensin II.
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As a result, pressure drops in large arterial vessels (mainly the arteries). In capillaries, the blood flow, on the contrary, is amplified. The maximum reduction in blood pressure is observed, about six hours after taking the dose. Treatment drug improves heart health. With prolonged use, hypertrophied myocardium returns to its normal state. In addition, this drug has the ability to reduce the excretion of protein in the urine. This occurs due to the improvement of filter fabric in the kidneys.
Lisinopril is used for.
- Failure of cardiac function in the chronic form;
- Early treatment of myocardial infarction is to maintain the function of the left ventricle;
- Diabetic kidney damage.
Release lisinopril tablets with different concentration of the active substance. Start treatment with low doses, which are then adjusted depending on efficiency. Manual of drug lisinopril notes that for patients who take diuretics need to be stopped a few days before using this medicine. Otherwise, maybe too severe drop in blood pressure. Therefore, the patient should be under medical supervision for six hours after taking a dose of drug (in order, if necessary, to adjust the condition of the patient, maintaining a normal level of pressure).
Patients with impaired renal function and elderly patients required correction quantity of the drug. In these situations, the exchange of lisinopril broken. For the use of this drug across a range of indications developed separate standards that are outlined in the annotation of Lisinopril.
The use of this medication should not depend on food intake.
Lisinopril is contraindicated when.
- Cases of angioneurotic edema, reactions to drugs of the group of ACE inhibitors;
- Possible angioedema (hereditary);
- Other types of intolerance to the drug;
- Treatment of minor patients;
- The renal blood flow;
- Renal failure;
- Coronary heart disease;
- Blood circulation disorders of the myocardium;
- Autoimmune lesions;
- Some violations of water-salt balance.
Side effects and overdose Lisinopril.
Most often patients who started therapy with this medicine, complaining of a cough, headache, nausea, and diarrhea, General weakness, skin rash, too much pressure drop. Also, in rare cases, there are side effects associated with disorders of the various body systems.
Lisinopril blood pressure❤ decreases expressed. The patient dry mouth, urinary retention occurs, and constipation. Also, there is irritability, anxiety, drowsiness. The treatment consists in restoring water-salt balance, control and maintain pressure. Possible hemodialysis.
Reviews about Lisinopril.
Quite often reviews about drug show that the change of body reaction to this drug is done gradually. For example, first the patient is satisfied with the effect of the medications, it takes a long time (from six months to several years). But later he shows side effects of the drug:
-Saw lisinopril three years. Pressure controlled well. But recently began to fall and a dry cough.
-Took lisinopril, for about six months. Winter started coughing. At first thought, it was the flu. But then I realized that react to the medicine.
Generally, when you experience such reactions to treatment with ACE inhibitors, the doctor will make a decision on the replacement drug. However, be sure to consult a specialist don’t change medication on your own.
There are also positive opinions about Lisinopril:
-For four years my hypertension had tried a variety of drugs (Noliprel, Normodipine, Losap etc). Lisinopril and only finally gave me the feeling of normal well-being. And by all indications keeps the pressure normal.
Other patients, this therapy does not bring the desired result.
In general, the choice of drugs affecting the cardiovascular system should be made by a physician. Even in this case, possible errors often the patient has, literally, experience the effect of several drugs until you find the best treatment regimen. Therefore, it is impossible to describe lisinopril, how successful or mostly ineffective medicine its activity is evaluated individually.