Lariam is an anti-malarial drug with antibacterial effect. The active ingredient mefloquine. A drug used to treat mild and severe forms of malaria. Also, the product can be used as a prophylactic agent in cases of emergency treatment (when medical help is not available). It is not recommended to assign Lariam patients suffering from acute psychoses and epilepsy. Do not use the drug in individuals with hypersensitivity to its components, as well as pregnant and lactating women.
In the case of diagnosing a patient’s liver failure, to receive Lariam should be treated with caution. The drug taking inside after eating, squeezed 200 ml of pure water. The daily dose prescribed by the doctor should be divided into three steps, pills can be crushed. Possible side effects as nausea and diarrhea.
Mefloquine has a bitter and slightly burning taste. The tablets should be swallowed whole. When administered to children or people who cannot swallow the tablet whole, it can be crushed and dissolved in a small amount of water, milk or your favorite beverage.
The total dose of drug Lariam depending on the body mass of the patient and distribution of the drug to the techniques shown in the table.
|Body weight, kg||The total dose, pills||Dose distribution on techniques, pills*|
|20-30||2-3||2 + 1|
|30-45||3-4||2 + 2|
|45-60||5||3 + 2|
|>60||6||3 + 2 + 1|
* If you divide the total therapeutic dose into 2-3 doses (e.g. 3 + 1; 3 + 2 or 3 + 2 + 1 tablet) every 6-8 hours, it can reduce the frequency or severity of side effects of the drug.
Special instructions Lariam.
Lariam can increase the risk of seizures in patients with epilepsy. Therefore, such patients the drug can be administered only for the purpose of treatment and in the presence of absolute indications for its use (see also “Interactions”).
After quinine or hinidina take mefloquine can be no earlier than 12 hours. For the preventive purpose for a long time (taking the drug for more than 1 year junk) requires periodic analysis of indicators of liver function and ophthalmologic examination.
Due to the risk of potentially life-threatening QT prolongation cannot be assigned halofantrin together with Lariam or after it. Data on the use of Lariam after halofantrine no.
With the development of anxiety, depression, restlessness or disturbance of consciousness during the prophylactic use of Lariam the drug should be discontinued.
Experience Lariam in children under the age of 6 months or weighing things less than 5 kg is limited.
Influence on ability to driving of motor transport and work with machines and mechanisms
During treatment should refrain from driving vehicles and activities potentially hazardous activities, require high concentration and psychomotor speed reactions.