Tamoxifen is a hormonal drug that is an antagonist of estrogen. Once in the human body, its active component binds to a specific receptor and prevents the absorption of them of estrogen. Thus, Tamoxifen slows the growth of estrogen-dependent tumors.
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Besides, it has effects similar to estrogen, positively affecting the state of the endometrium of the uterus, musculoskeletal, cholesterol levels in the blood.
Prescribe Tamoxifen at estrogen-dependent tumors, breast cancer, uterine cancer, melanomas, carcinomas of the prostate, sarcomas and some other types of tumors. Also, this drug can be used for hormone replacement therapy after removal of the ovaries or in the absence of ovulation.
Produce Tamoxifen in pill form. Manual of drug reports that are first assigned to a smaller dose, which, after some time, increased to the required. The basic principle of the dosing Tamoxifen is the individual selection.
Not recommended treatment Tamoxifen people with individual intolerance, severe deficiencies of hematopoiesis. Diabetes, ophthalmic disorders, also should be cause for special caution during therapy with this medication. Separately, it should be noted that women in childbearing age, up until menopause, you should apply severe birth-control measures without the use of hormonal contraceptive drugs. The threat to pregnancy is a period of treatment with Tamoksifenom and two months after its completion. Also, at this time should refrain from breastfeeding an infant.
Side effects and overdose Tamoxifen.
The annotation of the medication provided that the number of adverse effects from Tamoxifen is less than that of the hormonal drugs which also are used in the treatment of cancer. However, the described effects such as hot flashes, heat, bleeding, itching – they are due to antiestrogen effect of the drug. Can occur the common adverse effects – dyspepsia, edema, hair loss, and so on. The basic rule for correction Tamoxifen therapy accompanied by side effects is decrease the dose. This drug should be accompanied by medical and laboratory control. Cases of an overdose not described, but it is assumed the manifestation of the action similar to the action of estrogen. Measures should be taken symptomatic.
Reviews about Tamoxifen.
Since this drug is used in the treatment of such severe and complicated processes as cancer or hormonal disorders, including disruptions of the menstrual cycle, the effects on the organism of each patient is very individual and evaluate the impact on the reviews about it not quite right.
There are often questions about the impact of Tamoxifen on a particular symptom, its role in the development of a particular state. To discuss the need for treatment comes to mind not many – we are talking often about life or death of the patient.
However, there are egregious cases of the use of – fans of bodybuilding build muscle mass with the help of hormonal preparations. They often try to “hit the estrogenic action of some anabolic steroids this means. It should be noted that such an invasion in their own health – always ends in tears. If the consequences do not come soon, they must manifest itself throughout life.
It is obvious that in some conditions, necessary. And this fact practically excludes the evaluation approach – this drug is good or bad. It is important not to cripple themselves thoughtless use of medicines, for the sake of some elusive goals.