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Composition and form. Prednisone. Tablets (5 mg, 20 mg, 50 mg); solution for injection (1 ml-30 mg). Prednisolone acetate. Suspension for injection (1 ml-25 mg). Prednisolone gemisuktinat sodium. Dry chemical injection (1 ampoule-10 mg, 25 mg, 50 mg, 250 mg). Prednisolone. Ointment (1-5 mg). Prednisolone acetate. Ophthalmic Suspension (1 ml-5 mg).

GKS.

The anti-inflammatory and anti-allergic effect has antishock and immunosuppressive activity. Effect on different types of metabolism increases blood glucose, provides kata bo-hydraulic action contributes to the redistribution of adipose tissue can cause osteoporosis, delaying sodium ions and water in the body, increases ad. Effect on inflammation in connective tissue and reduces the possibility of education-pub co fabrics. The local application has anti-inflammatory, anti-allergic and antièkssu-dativnoe action.
For the reception inside and\/m. Rheumatism, Rheumatoid Arthritis, Dermatomyositis, polyarteritis, Scleroderma, ankylosing spondylitis. BAH. Asthma status. Acute and chronic allergic diseases. Addison’s disease, acute adrenocortical insufficiency, adrenogenital′-s ‘ syndrome. Hepatitis, hepatic coma, gipoglikemi environmental condition, lipoidal nephrosis. Agranulocytosis, various forms of leukemia, chlamydia, thrombocytopenic purpura, hemolytic anemia. Chorea minor. Vesicular disease, eczema, itching, èksfolia-rate Dermatitis, psoriasis, eczema, seborej scrapie-associated Dermatitis, Lupus Erythematosus, erythrodermic, psoriasis, alopecia. For Ophthalmology: allergic, chronic and atypical conjunctivitis and blepharitis; corneal inflammation in the mucosa intact; acute and chronic inflammation of the anterior segment of the choroid, sclera, and èpisklery; sympathetic branch inflammation of the eyeball; after injuries and operations during prolonged stimulation of the eyeballs. For intra-articular Introduction: Chronic Polyarthritis, post-traumatic arthritis, osteoarthritis of large joints, rheumatic individual joints, arthritis. For an introduction into the tissue infiltration: epikondilit, tend wag init, bursitis, plečelo-syrup PERIARTHRITIS, Keloids, ischialgia, Dupuytren’s Contracture, rheumatic and similar joints and various tissues.
The Application.For the reception inside. When replacement therapy in adults, the initial dose is 20-30 mg\/day supporting dose is 5-10 mg\/SUT. If necessary, the initial dose may be 15-100 mg\/day supporting-5-15 mg\/day. The daily dose should be reduced gradually. For children initial dose of 1-2 mg\/kg\/day in 4-6 receptions supporting-0.3-0.6 mg\/kg\/SUT. For injection. When the\/m a dose, the multiplicity, and duration of application are determined individually. When vnutrisustavnom the introduction of large joints applied dose-25-50 mg, for joints of average size is 10-25 mg, for small joints is 5-10 mg. For an introduction into the tissue infiltration depending on the severity of the condition and size of the affected area, apply the dose from 5 up to 50 mg. The product is not intended for on\/in the introduction. Within days the medication recommended in view of the Ric-kaid nogo rhythm endogenous secret CORTICOSTEROIDS range from 6 to 8 h am. During treatment (particularly long-term) need to monitor ophthalmologist, monitoring ad and EB. as well as picture peripheral blood and blood sugar; in order to reduce side effects, you can assign anabolic steroids, antibiotics, as well as to increase the intake of potassium in the body (diet, drugs potassium). When references to psychosis in people with a history of prednisone in large doses prescribed under the strict supervision of a physician. Diabetes appoints only when absolute testimony or to prevent the alleged resistance to insulin. When nonspecific infections used with caution and provided simultaneous chemo-or antibiotic Tera-FDI. When the latent forms of tuberculosis prednisone can be used only in combination with anti-TB means. It is recommended to clarify the need for the introduction of ACTH after a course of prednisolone (after the skin test!). When Addison disease should avoid simultaneous application with a barbiturate. During pregnancy (especially in the first trimester) the drug is used for health reasons. The ointment should not be used for more than 14 days. In the case of drugs in common or pink graph may exacerbate diseases for local use. In Ophthalmology: Eye medication in the form of suspended matter buried in the bag kong ungual NY by 1-2 drops 3 p\/day; the course of treatment is not more than 14 days. In Dermatology: rubbing ointment 1-3 r\/d in the affected areas of skin.

Side effects.

Reduced resistance to infection; delayed wound healing; the syndrome itsenko-Kushinga; increased body mass index; increased acidity gastric juice ul′cerogen-Noe action on the organs of the SAR; water and electrolyte balance; increased excretion of potassium, the delay sodium in the body with the formation of edema; AG; improvement of blood coagulability; osteoporosis, aseptic necrosis of the bones; Hyperglycemia, up to the development of steroid diabetes, exhaustion (up to atrophy) of the adrenal cortex; nitrogenous negative balance; steroid cataract, provoking glaucoma latent mental disorders. In zacapawanyi in the kongungualny bag may lack burning. Using sunscreen, you may experience the Steroid Acne, Purpura, teleangioèk-tasius, as well as burning, itching, irritation, dryness of skin; with long-term use and\/or causing long-surface may develop re-zorb ti no go action. After the end of treatment, you may experience withdrawal symptoms, nadpočeč satellite failure, as well as the exacerbation of the disease, which was appointed as prednisone.

Contraindications.

peptic ulcers, osteoporosis, a disease itsenko-Kushinga, the propensity to embolism, MON. heavy AG. systemic mikozy, viral infection, vaccination, the active form of tuberculosis, glaucoma, productive symptoms of mental diseases, hypersensitivity to the drug. For infiltration introduction in lesions of skin and tissues: chickenpox, specific infections, mycoses, local reaction to the vaccination. In Ophthalmology: viral and bacterial diseases of the eye, primary glaucoma, corneal disease with epithelial damage. In Dermatology: bacterial, viral, fungal skin infections, tuberculosis, syphilis, tumors of the skin.

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