Nolvadex release form for shell Pill 10 and 20 mg drugs. Antiestrogennoe (prevents formation of female sex hormones), protivoopujolevoe. Pharmacodynamics and pharmacokinetics Pharmacodynamics LF Nolvadex is a nonsteroidal estrogen antagonist. Specifically binds with estrogenic receptors in peripheral and in tumor tissues. Thus, eliminates the influence of the estrogens produced in the body and stimulate the growth of cancer cells.
DISCOUNT CODE “669069”
After taking a single dose a few weeks to continue the ability to block estrogen. Ovulation in women, men with oligospermia increases levels of LH and FSH.
LF Pharmacokinetics if ingestion is rapidly absorbed, and through 5-7 hours maximum concentration in the blood is. At 99% is associated with the blood protein (albumin). Excretion occurs dwuhfazno: initial t 1/2 from 8 to 14 h, the final T 1/2-7 days. Return with faeces, only a small portion of the urine.
Nolvadex is used when:
LF Nolvadex Pills Contraindications contraindicated in:
LF Nolvadex side effects can cause undesirable reactions:
- gastrointestinal disorders and nausea;
- uterine bleeding. Endometrial hyperplasia. uterine Fibroma. itching of the vulva;
- fluid retention in the body;
- thrombocytopenia, lakopenia;
- bone pain;
- changes in the retina of the eye;
Nolvadex instructions (method and dosage).
Nolvadex Pills taken orally is not liquid, squeezed water. May receive the entire dose at once in the morning or for two receptions in the morning and in the evening. When breast cancer is prescribed 20-40 mg, endometrium cancer-30-40 mg. Maximum SD-40 mg. Treatment are long, often in combination with zitostaticescoy and radiation therapy.
during treatment, control blood clotting, leukocytes, platelets, the level of calcium in the blood, the liver. Eye examination is conducted quarterly and gynaecological examination. The drug is ineffective when there metastases (especially liver).
LF Overdose is manifested by increased side effects. Symptomatic treatment. There is no antidote.
LF Interaction Nolvadex (Tamoxifen) do anti effect. Simultaneous reception èstrogensoderžaŝimi with contraceptives decreases both HP. LF-gistaminovh receptors H2 blockers and antacids can cause premature dissolution of the enteric tablets, so the time between taking these drugs should be 2:00.